Calcific Aortic Valve Disease Ed. By Elena Aikawa

Calcific Aortic Valve Disease Ed. By Elena Aikawa
by Elena Aikawa / / / PDF


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This book covers the contemporary understanding of basic valve biology and the mechanisms of Calcific Aortic Valve Disease (CAVD), provides novel insights into the genetics, proteomics, and metabolomics of CAVD, depicts new strategies in heart valve tissue engineering and regenerative medicine, and explores current treatment approaches. This book will enable readers to comprehend our current knowledge and focus on the possibility of preventing disease progression in the future. Preface Section 1 Biology and Function of Normal Aortic Valve 1 Extracellular Matrix Organization, Structure, and Function 2 Anatomy and Function of Normal Aortic Valvular Complex Section 2 Mechanisms of Calcific Aortic Valve Disease 3 Developmental Pathways in CAVD 4 Notch Signaling in Congenital and Acquired Aortic Valve Disease 5 Role of MicroRNAs in Cardiovascular Calcification Section 3 Genetics, Proteomics and Metabolomics of Calcific Aortic Valve Disease 6 Proteomics and Metabolomics in Aortic Stenosis: Studying Healthy Valves for a Better Understanding of the Disease 7 Genetics of Bicuspid Aortic Valve and Calcific Aortic Valve Disease Section 4 New Strategies in Heart Valve Tissue Engineering and Regenerative Medicine 8 The Immune Response in In Situ Tissue Engineering of Aortic Heart Valves 9 Cutting-Edge Regenerative Medicine Technologies for the Treatment of Heart Valve Calcification Section 5 Bicuspid Aortic Valve 10 Bicuspid Aortic Valve 11 The Bicuspid Aortic Valve Section 6 Current Treatment Approaches 12 Surgical Valve Replacement (Bioprosthetic vs. Mechanical) 13 Current Treatment Options in Aortic Stenosis 14 Stentless Bioprosthess for Aortic Valve Replacement in Calcific Aortic Stenosis 15 New Therapeutic Approaches to Conventional Surgery for Aortic Stenosis in High-Risk Patients 16 Indications for Transcatheter Aortic Valve Implantation 17 Aortic Valve Replacement for Calcified Aortic Valves 18 Congenital Aortic Stenosis in Children

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