Chemical Biology Ed. By Deniz Ekinci
by Deniz Ekinci /
2015 / English / PDF
22.1 MB Download
This book contains an overview focusing on the research area of protein purification, enzymology, vitamins, antioxidants, biotransformation, gene delivery, signaling, regulation and organization. Particular emphasis is devoted to both theoretical and experimental aspects. The textbook is written by international scientists with expertise in synthetic chemistry, protein biochemistry, enzymology, molecular biology, drug discovery and genetics many of which are active chemical, biochemical and biomedical research. The textbook is expected to enhance the knowledge of scientists in the complexities of chemical and biological approaches and stimulate both professionals and students to dedicate part of their future research in understanding relevant mechanisms and applications of chemical biology. Preface Part 1 Protein Purification & Enzymology 1. Protein Purification 2. The Problems Associated with Enzyme Purification 3. Nicotinamide Phosphoribosyltransferase Inhibitors 4. Cofactor Recycling Using a Thermostable NADH Oxidase 5. Analyses of Sequences of (p/a) Barrel Proteins Based on the Inter-Residue Average Distance Statistics to Elucidate Folding Processes 6. Functional Implication Guided by Structure- Based Study on Catalase - Peroxidase (KatG) from Haloarcula Marismortui Part 2 Vitamins & Antioxidants 7. Effects of Dietary Fortification of Vitamin A and Folic Acid on the Composition of Chicken Egg 8. Mitochondria and Antioxidants: The Active Players in Islet Oxidative Stress 9. Nitric Oxide Signaling During Senescence and Programmed Cell Death in Leaves 10. Menaquinone as Well as Ubiquinone as a Crucial Component in the Escherichia coli Respiratory Chain Part 3 Biotransformation & Gene Delivery 11. Genetically Modified Baker's Yeast Saccharomvces cerevisiae in Chemical Synthesis and Biotransformations 12. Animal Models for Hydrodynamic Gene Delivery Part 4 Hormones and Receptors 13. Role of p-Arrestins in Endosomal Sorting of G Protein-Coupled Receptors 14. Structure and Function of the Lipolysis Stimulated Lipoprotein Receptor 15. Ghrelin. a Gastric Hormone with Diverse Functions Part 5 Organization & Regulation 16. Polysialylation of the Neural Cell Adhesion Molecule: Setting the Stage for Plasticity Across Scales of Biological Organization 17. What Does Maurocalcine Tell Us About the Process of Excitation-Contraction Coupling? 18. 13C-Metabolic Flux Analysis and Metabolic Regulation 19. QCM as Cell-Based Biosensor
