Drug Delivery: An Integrated Clinical And Engineering Approach
by Yitzhak Rosen /
2017 / English / PDF
39.6 MB Download
Integrating the clinical and engineering aspects of drug
delivery, this book offers a much needed comprehensive overview
and patient-oriented approach for enhanced drug delivery
optimization and advancement. Starting with an introduction to
the subject and pharmacokinetics, it explores advances for such
topics as oral, gastroretentive, intravitreal, and intrathecal
drug delivery, as well as insulin delivery, gene delivery, and
biomaterials-based delivery systems. It also describes drug
delivery in cancer, cardiac, infectious diseases, airway
diseases, and obstetrics and gynecology applications. Examining
special clinical states requiring innovative drug delivery
modifications, such as hypercoagulability often seen in
pregnancy, cancer, and autoimmune diseases, the book also
discusses methods for improved drug delivery in clinical settings
using clinical end points, clinical trials, simulations, and
other venues. It also describes the latest drug delivery advances
involving nanomaterials, NEMS and MEMS devices, hydrogels,
microencapsulation, lipids, stem cells, patches, and ultrasound.
The book is rounded out by a chapter on the FDA regulatory and
bioethical challenges involved in advancing drug delivery.
Integrating the clinical and engineering aspects of drug
delivery, this book offers a much needed comprehensive overview
and patient-oriented approach for enhanced drug delivery
optimization and advancement. Starting with an introduction to
the subject and pharmacokinetics, it explores advances for such
topics as oral, gastroretentive, intravitreal, and intrathecal
drug delivery, as well as insulin delivery, gene delivery, and
biomaterials-based delivery systems. It also describes drug
delivery in cancer, cardiac, infectious diseases, airway
diseases, and obstetrics and gynecology applications. Examining
special clinical states requiring innovative drug delivery
modifications, such as hypercoagulability often seen in
pregnancy, cancer, and autoimmune diseases, the book also
discusses methods for improved drug delivery in clinical settings
using clinical end points, clinical trials, simulations, and
other venues. It also describes the latest drug delivery advances
involving nanomaterials, NEMS and MEMS devices, hydrogels,
microencapsulation, lipids, stem cells, patches, and ultrasound.
The book is rounded out by a chapter on the FDA regulatory and
bioethical challenges involved in advancing drug delivery.