Kidney Cancer: Recent Results Of Basic And Clinical Research (contributions To Nephrology)
by O. Hino /
1999 / English / PDF
3 MB Download
Cancer is above all a heritable disorder of somatic cells and gene
expression, but environment is also involved in its origin.
Hereditary kidney cancer should prove valuable to understand the
mechanisms of disease and to the development of therapeutic
measures. Recently, scientists have succeeded in cloning and
identifying the genes responsible for the following familial kidney
cancers: von Hippel-Lindau disease, papillary renal cell carcinoma,
tuberous sclerosis and Wilms tumor (all autosomal dominant). This
book brings together some of the most recent advances made with
respect to kidney cancers: Leading investigators present recent
results on VHL, MET, TSC1 and TSC2 and WT1 genes, among others, as
well as on environmentally induced kidney cancers (caused by
long-term hemodialysis or induced chemically) and their treatments
(surgery and gene therapy), providing an excellent survey of this
field. This publication will be of interest to both researchers and
clinicians concerned with cancer of the kidney.
Cancer is above all a heritable disorder of somatic cells and gene
expression, but environment is also involved in its origin.
Hereditary kidney cancer should prove valuable to understand the
mechanisms of disease and to the development of therapeutic
measures. Recently, scientists have succeeded in cloning and
identifying the genes responsible for the following familial kidney
cancers: von Hippel-Lindau disease, papillary renal cell carcinoma,
tuberous sclerosis and Wilms tumor (all autosomal dominant). This
book brings together some of the most recent advances made with
respect to kidney cancers: Leading investigators present recent
results on VHL, MET, TSC1 and TSC2 and WT1 genes, among others, as
well as on environmentally induced kidney cancers (caused by
long-term hemodialysis or induced chemically) and their treatments
(surgery and gene therapy), providing an excellent survey of this
field. This publication will be of interest to both researchers and
clinicians concerned with cancer of the kidney.