Role Of Capsaicin In Oxidative Stress And Cancer Diet & Cancer 3 (diet And Cancer)
by Sanjay K. Srivastava /
2013 / English / PDF
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This book describes the mechanism of the anti-cancer effects of capsaicin including the involvement of cytochrome P-450 in the bioactivation identification of mitochondria as the key target site for oxidative stress involvement of mitochondrial respiratory chain in the production of ROS prevention of chemically-induced carcinogenesis, discussion on TRPV-1 receptor mediated or independent anti-cancer effects identification of p53 activation as a possible mechanism involvement of Cox-2 in apoptosis, suppression of transcription factors such as NF-kB and STAT-3 inhibition of cell survival pathways including PI3K/Akt and the involvement of intrinsic mitochondrial cell death pathway.
