Adiposity: Omics And Molecular Understanding
by Jan Oxholm Gordeladze /
2017 / English / PDF
100 MB Download
This book is the second in a series of two, featuring the "Adiposity: Omics and Molecular Understanding", serving as an introduction to modern views on how the adipocytes are reciprocally interacting with organ systems in order to explain the biology of the body's fat cells and how they are integrated with other organ systems, like muscle cells and the liver, in order to control the lipid metabolism in our bodies, to finally preserve a positive balance between white and brown/beige adipocyte tissues (WAT and BAT).
The understanding of the "omics" of obesity will therefore enable clinicians and researchers to better pursue the untoward incidents of metabolic deviations from a defined and health-bringing homeostasis, with fully responding WAT and BAT, being able to preserve a healthy balance between fat-producing and fat-metabolizing tissues for the benefit of the host, and thus longevity (optimal health with healthy, well-functioning organ systems) throughout a lifetime.
Preface
1 Introductory Chapter: Obesity—“OMICS” and Endocrinology
2 The Omics of Obesity
3 Usefulness of Obese Animal Models in Antiobesity Drug Development
4 Obesity and Its Influence on Mediators of Inflammation: Clinical Relevance of C-Reactive Protein in Obese Subjects
5 Adiponectin, Inflammation and Cardiometabolic Risk Factors in Paediatric Obese Patients: Impact of Interventional Studies
6 Obesity Peptide: Prokineticin
7 The Role of Adipocyte Hypertrophy and Hypoxia in the Development of Obesity-Associated Adipose Tissue Inflammation and Insulin Resistance
8 Vitamin D Status in Obesity: Relation with Expression of Vitamin D Receptor and Vitamin D Hydroxylation Enzymes in Subcutaneous and Visceral Adipose Tissue
9 Immunometabolism in Obesity
10 Obesity and Coronary Artery Disease
11 The Pediatric Obesity Epidemic and the Role of the Corporation: Why Work Conditions and Faith in Meritocracy Matter
12 New Thoughts on Pediatric Genetic Obesity: Pathogenesis, Clinical Characteristics and Treatment Approach
13 Human Gut Microbiota and Obesity During Development
