Advances In Targeted Cancer Therapy (progress In Drug Research)
by Richard M. Schultz /
2005 / English / PDF
1.7 MB Download
This volume is the first book to cover the general topic of
targeted cancer therapy. It presents a range of targets such as
tumor angiogenesis, cell cycle control and cell signalling,
COX-2, apoptosis/cell survival, invasion and metastasis and
approaches like kinase inhibitors, antisense, and antibody-based
therapeutics. The emphasis is on preclinical development,
including target validation, development of biomarkers,
strategies for combination approaches, and development of
resistance. The particular challenges involved in translating
these data to clinical application are discussed.
This volume is the first book to cover the general topic of
targeted cancer therapy. It presents a range of targets such as
tumor angiogenesis, cell cycle control and cell signalling,
COX-2, apoptosis/cell survival, invasion and metastasis and
approaches like kinase inhibitors, antisense, and antibody-based
therapeutics. The emphasis is on preclinical development,
including target validation, development of biomarkers,
strategies for combination approaches, and development of
resistance. The particular challenges involved in translating
these data to clinical application are discussed.
This volume should be of broad general interest to researchers
and clinicians involved in cancer therapy as well as other
scientists interested in current strategies for cancer treatment.
This volume should be of broad general interest to researchers
and clinicians involved in cancer therapy as well as other
scientists interested in current strategies for cancer treatment.
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