Angiogenesis: In Vivo Systems, Part A, Volume 444 (methods In Enzymology)
by David A. Cheresh /
2008 / English / PDF
11.2 MB Download
Angiogenesis is the growth of new blood vessels and is an important
natural process in the body. A healthy body maintains a perfect
balance of angiogenesis modulators. In many serious disease states,
however, the body loses control over angiogenesis. Diseases that
are angiogenesis-dependent result when blood vessels either grow
excessively or insufficiently. Understanding how angiogenesis
"works" and how to control it, will have massive implications on
the management, treatments, and ultimately the prevention of many
common (and not so common) diseases.
Angiogenesis is the growth of new blood vessels and is an important
natural process in the body. A healthy body maintains a perfect
balance of angiogenesis modulators. In many serious disease states,
however, the body loses control over angiogenesis. Diseases that
are angiogenesis-dependent result when blood vessels either grow
excessively or insufficiently. Understanding how angiogenesis
"works" and how to control it, will have massive implications on
the management, treatments, and ultimately the prevention of many
common (and not so common) diseases.
Angiogenesis cuts across virtually every discipline. The
Angiogenesis Foundation identified angiogenesis as a "common
denominator" in our most serious diseases. Excessive angiogenesis
occurs in diseases such as cancer, diabetic blindness, age-related
macular degeneration, rheumatoid arthritis, psoriasis, and many
other conditions. Insufficient angiogenesis occurs in diseases such
as coronary artery disease, stroke, and delayed wound
healing.
Angiogenesis cuts across virtually every discipline. The
Angiogenesis Foundation identified angiogenesis as a "common
denominator" in our most serious diseases. Excessive angiogenesis
occurs in diseases such as cancer, diabetic blindness, age-related
macular degeneration, rheumatoid arthritis, psoriasis, and many
other conditions. Insufficient angiogenesis occurs in diseases such
as coronary artery disease, stroke, and delayed wound
healing.
* Tried-and-tested techniques written by researchers that developed
them, used them, and brought them to fruition.
* Tried-and-tested techniques written by researchers that developed
them, used them, and brought them to fruition.
* Provides the "builder's manual" for essential techniques. This is
a one-stop shop that eliminates needless searching among untested
techniques.
* Provides the "builder's manual" for essential techniques. This is
a one-stop shop that eliminates needless searching among untested
techniques.
* Includes step-by-step methods for understanding the cell and
molecular basis of wound healing, vascular integrin signaling,
mechanical signaling in blood vessels, and vascular proteomics
* Includes step-by-step methods for understanding the cell and
molecular basis of wound healing, vascular integrin signaling,
mechanical signaling in blood vessels, and vascular proteomics