Autophagy At The Cell, Tissue And Organismal Level (springerbriefs In Cell Biology)
by Eleftherios Karanasios /
2016 / English / PDF
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This book provides an expert summary of autophagy, a relatively
new but rapidly expanding field of biomedical science with
important implications in health and disease. After a historical
review ranging up to the identification of autophagy genes in
mammals, the authors discuss the signaling pathways that regulate
autophagy, the mechanism of autophagosome formation and the
physiological roles of autophagy in development, ageing,
neurodegeneration, immune function and cell differentiation. A
comprehensive list of useful antibodies for studying autophagy
compiled as a community effort is included at the end. The book
is intended for newcomers to the field, as well as more
experienced researchers looking for a condensed but comprehensive
introduction to the physiological function and regulation of the
autophagic pathway in mammalian organisms.
This book provides an expert summary of autophagy, a relatively
new but rapidly expanding field of biomedical science with
important implications in health and disease. After a historical
review ranging up to the identification of autophagy genes in
mammals, the authors discuss the signaling pathways that regulate
autophagy, the mechanism of autophagosome formation and the
physiological roles of autophagy in development, ageing,
neurodegeneration, immune function and cell differentiation. A
comprehensive list of useful antibodies for studying autophagy
compiled as a community effort is included at the end. The book
is intended for newcomers to the field, as well as more
experienced researchers looking for a condensed but comprehensive
introduction to the physiological function and regulation of the
autophagic pathway in mammalian organisms.
