Biomarkers In Neoplastic Neuropathology
by Fausto Rodriguez /
2016 / English / PDF
3.7 MB Download
This book is a rich source of information on biomarkers applicable
to the pathology of neoplastic disorders of the brain. Thorough
descriptions are provided of the techniques currently available for
clinical and experimental evaluation of biomarkers in brain
neoplasms, including in situ hybridization, array-based methods,
methylation profiling, next-generation sequencing, and practical
gene panels. Incorporation of multiple biomarkers in the
development of molecular subgroups with biologic and therapeutic
relevance is also discussed. A section on biobanking covers the
equally important topic of optimal preservation of tissue and
includes consideration of ethical considerations raised by the use
of tissue obtained in clinical settings. The closing section
discusses the major categories of neoplastic disorders involving
the nervous system, with emphasis on diagnostic, prognostic, and
predictive biomarkers used in the pathologic evaluation of
different types of brain tumor.
This book is a rich source of information on biomarkers applicable
to the pathology of neoplastic disorders of the brain. Thorough
descriptions are provided of the techniques currently available for
clinical and experimental evaluation of biomarkers in brain
neoplasms, including in situ hybridization, array-based methods,
methylation profiling, next-generation sequencing, and practical
gene panels. Incorporation of multiple biomarkers in the
development of molecular subgroups with biologic and therapeutic
relevance is also discussed. A section on biobanking covers the
equally important topic of optimal preservation of tissue and
includes consideration of ethical considerations raised by the use
of tissue obtained in clinical settings. The closing section
discusses the major categories of neoplastic disorders involving
the nervous system, with emphasis on diagnostic, prognostic, and
predictive biomarkers used in the pathologic evaluation of
different types of brain tumor.
