Chemokine Biology - Basic Research And Clinical Application: Vol. 1: Immunobiology Of Chemokines (progress In Inflammation Research)
by Bernhard Moser /
2005 / English / PDF
3.4 MB Download
Chemokines play an important role in recruiting inflammatory
cells into tissues in response to infection and inflammation.
They also play an important role in coordinating the movement of
T-cells, B-cells and dentritic cells, necessary to generate an
immune response (response to injury, allergens, antigens,
invading microorganisms). They selectively attract leukocytes to
inflammatory foci, inducing both cell migration and activation.
They are involved in various diseases, like atherosclerosis, lung
and skin inflammation, multiple sclerosis, or HIV.
Chemokines play an important role in recruiting inflammatory
cells into tissues in response to infection and inflammation.
They also play an important role in coordinating the movement of
T-cells, B-cells and dentritic cells, necessary to generate an
immune response (response to injury, allergens, antigens,
invading microorganisms). They selectively attract leukocytes to
inflammatory foci, inducing both cell migration and activation.
They are involved in various diseases, like atherosclerosis, lung
and skin inflammation, multiple sclerosis, or HIV.
Volume 1 of this two-volume set discusses the immunobiology of
chemokines. It is divided into two parts: a) cellular targets in
innate and adaptive immunity, and b) effector cell
traffic-unrelated functions. Together with volume 2, which
discusses the pathophysiology of chemokines, both volumes give a
comprehensive overview of chemokine biology.
Volume 1 of this two-volume set discusses the immunobiology of
chemokines. It is divided into two parts: a) cellular targets in
innate and adaptive immunity, and b) effector cell
traffic-unrelated functions. Together with volume 2, which
discusses the pathophysiology of chemokines, both volumes give a
comprehensive overview of chemokine biology.
