Computational Modeling Of Genetic And Biochemical Networks (computational Molecular Biology)
by James M. Bower /
2004 / English / PDF
4.3 MB Download
The advent of ever more sophisticated molecular manipulation
techniques has made it clear that cellular systems are far more
complex and dynamic than previously thought. At the same time,
experimental techniques are providing an almost overwhelming
amount of new data. It is increasingly apparent that linking
molecular and cellular structure to function will require the use
of new computational tools.
The advent of ever more sophisticated molecular manipulation
techniques has made it clear that cellular systems are far more
complex and dynamic than previously thought. At the same time,
experimental techniques are providing an almost overwhelming
amount of new data. It is increasingly apparent that linking
molecular and cellular structure to function will require the use
of new computational tools.
This book provides specific examples, across a wide range of
molecular and cellular systems, of how modeling techniques can be
used to explore functionally relevant molecular and cellular
relationships. The modeling techniques covered are applicable to
cell, developmental, structural, and mathematical biology;
genetics; and computational neuroscience. The book, intended as a
primer for both theoretical and experimental biologists, is
organized in two parts: models of gene activity and models of
interactions among gene products. Modeling examples are provided
at several scales for each subject. Each chapter includes an
overview of the biological system in question and extensive
references to important work in the area.
This book provides specific examples, across a wide range of
molecular and cellular systems, of how modeling techniques can be
used to explore functionally relevant molecular and cellular
relationships. The modeling techniques covered are applicable to
cell, developmental, structural, and mathematical biology;
genetics; and computational neuroscience. The book, intended as a
primer for both theoretical and experimental biologists, is
organized in two parts: models of gene activity and models of
interactions among gene products. Modeling examples are provided
at several scales for each subject. Each chapter includes an
overview of the biological system in question and extensive
references to important work in the area.