Drug Discovery And Development: From Molecules To Medicine Ed. By Omboon Vallisuta And Suleiman Olimat
by Omboon Vallisuta /
2015 / English / PDF
18.7 MB Download
This book demonstrates that various expertise are essential for drug discovery including synthetic or natural drugs, clinical pharmacology, receptor identification, drug metabolism, pharmacodynamic and pharmacokinetic research. The book covers diverse chapter topics in drug discovery: Natural Products as Sources of Leading Molecules in Drug Discovery; Oncology and Drug Discovery; Receptors Involvement in Drug Discovery; Management and Development of Drugs against Infectious Diseases; Advanced Methodology. Preface 1 The Evolving Role of Natural Products from the Tropical Rainforests as a Replenishable Source of New Drug Leads 2 Edible and Medicinal Mushrooms as Promising Agents in Cancer 3 Challenges of Patient Selection for Phase I Oncology Trials 4 Advanced Human In vitro Models for the Discovery and Development of Lung Cancer Therapies 5 Nuclear Receptor Modulators — Current Approaches and Future Perspectives 6 Lipids and Liposomes in the Enhancement of Health and Treatment of Disease 7 The Small Molecule Inhibitor of Protein Kinase Revolution for the Treatment of Rheumatoid Arthritis 8 Current Management and Novel Therapeutic Strategies to Combat Chronic Delta Hepatitis 9 Targeting Bacterial Persistence to Develop Therapeutics Against Infectious Disease 10 Assay Validation in High Throughput Screening - from Concept to Application 11 Structural Analogy — Direct Similarity Versus Topographical Complementarity 12 Clinical Trials in Paediatrics — Regulatory and Methodological Aspects 13 Intranasal Drug Administration — An Attractive Delivery Route for Some Drugs
