Fuzziness: Structural Disorder In Protein Complexes (advances In Experimental Medicine And Biology)
by Peter Tompa /
2012 / English / PDF
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Detailed characterization of fuzzy interactions will be of central
importance for understanding the diverse biological functions of
intrinsically disordered proteins in complex eukaryotic signaling
networks. In this volume, Peter Tompa and Monika Fuxreiter have
assembled a series of papers that address the issue of fuzziness in
molecular interactions. These papers provide a broad overview of
the phenomenon of fuzziness and provide compelling examples of the
central role played by fuzzy interactions in regulation of cellular
signaling processes and in viral infectivity. These contributions
summarize the current state of knowledge in this new field and will
undoubtedly stimulate future research that will further advance our
understanding of fuzziness and its role in biomolecular
interactions.
Detailed characterization of fuzzy interactions will be of central
importance for understanding the diverse biological functions of
intrinsically disordered proteins in complex eukaryotic signaling
networks. In this volume, Peter Tompa and Monika Fuxreiter have
assembled a series of papers that address the issue of fuzziness in
molecular interactions. These papers provide a broad overview of
the phenomenon of fuzziness and provide compelling examples of the
central role played by fuzzy interactions in regulation of cellular
signaling processes and in viral infectivity. These contributions
summarize the current state of knowledge in this new field and will
undoubtedly stimulate future research that will further advance our
understanding of fuzziness and its role in biomolecular
interactions.