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Genomics: The Science And Technology Behind The Human Genome Project
by Charles R. Cantor /
1999 / English / PDF
5.6 MB Download
A unique exploration of the principles and methods underlying the
Human Genome Project and modern molecular genetics and
biotechnology-from two top researchers
A unique exploration of the principles and methods underlying the
Human Genome Project and modern molecular genetics and
biotechnology-from two top researchers
In Genomics, Charles R. Cantor, former director of the Human
Genome Project, and Cassandra L. Smith give the first integral
overview of the strategies and technologies behind the Human
Genome Project and the field of molecular genetics and
biotechnology. Written with a range of readers in mind-from
chemists and biologists to computer scientists and engineers-the
book begins with a review of the basic properties of DNA and the
chromosomes that package it in cells. The authors describe the
three main techniques used in DNA analysis-hybridization,
polymerase chain reaction, and electrophoresis-and present a
complete exploration of DNA mapping in its many different forms.
By explaining both the theoretical principles and practical
foundations of modern molecular genetics to a wide audience, the
book brings the scientific community closer to the ultimate goal
of understanding the biological function of DNA. Genomics
features:
In Genomics, Charles R. Cantor, former director of the Human
Genome Project, and Cassandra L. Smith give the first integral
overview of the strategies and technologies behind the Human
Genome Project and the field of molecular genetics and
biotechnology. Written with a range of readers in mind-from
chemists and biologists to computer scientists and engineers-the
book begins with a review of the basic properties of DNA and the
chromosomes that package it in cells. The authors describe the
three main techniques used in DNA analysis-hybridization,
polymerase chain reaction, and electrophoresis-and present a
complete exploration of DNA mapping in its many different forms.
By explaining both the theoretical principles and practical
foundations of modern molecular genetics to a wide audience, the
book brings the scientific community closer to the ultimate goal
of understanding the biological function of DNA. Genomics
features:Topical organization within chapters for easy reference
Topical organization within chapters for easy referenceA discussion of the developing methods of sequencing, such as
sequencing by hybridization (SBH) in which data is read through
words instead of letters
A discussion of the developing methods of sequencing, such as
sequencing by hybridization (SBH) in which data is read through
words instead of lettersDetailed explanations and critical evaluations of the many
different types of DNA maps that can be generated-including
cytogenic and restriction maps as well as interspecies cell
hybrids
Detailed explanations and critical evaluations of the many
different types of DNA maps that can be generated-including
cytogenic and restriction maps as well as interspecies cell
hybridsInformed predictions for the future of DNA sequencing
Informed predictions for the future of DNA sequencing