High-dimensional Single Cell Analysis: Mass Cytometry, Multi-parametric Flow Cytometry And Bioinformatic Techniques (current Topics In Microbiology And Immunology)
by Harris G. Fienberg /
2014 / English / PDF
6.9 MB Download
This volume highlights the most interesting biomedical and
clinical applications of high-dimensional flow and mass
cytometry. It reviews current practical approaches used to
perform high-dimensional experiments and addresses key
bioinformatic techniques for the analysis of data sets involving
dozens of parameters in millions of single cells. Topics include
single cell cancer biology; studies of the human immunome;
exploration of immunological cell types such as CD8
This volume highlights the most interesting biomedical and
clinical applications of high-dimensional flow and mass
cytometry. It reviews current practical approaches used to
perform high-dimensional experiments and addresses key
bioinformatic techniques for the analysis of data sets involving
dozens of parameters in millions of single cells. Topics include
single cell cancer biology; studies of the human immunome;
exploration of immunological cell types such as CD8+
+ T
cells; decipherment of signaling processes of cancer; mass-tag
cellular barcoding; analysis of protein interactions by proximity
ligation assays; Cytobank, a platform for the analysis of
cytometry data; computational analysis of high-dimensional flow
cytometric data; computational deconvolution approaches for the
description of intracellular signaling dynamics and hyperspectral
cytometry. All 10 chapters of this book have been written by
respected experts in their fields. It is an invaluable reference
book for both basic and clinical researchers.
T
cells; decipherment of signaling processes of cancer; mass-tag
cellular barcoding; analysis of protein interactions by proximity
ligation assays; Cytobank, a platform for the analysis of
cytometry data; computational analysis of high-dimensional flow
cytometric data; computational deconvolution approaches for the
description of intracellular signaling dynamics and hyperspectral
cytometry. All 10 chapters of this book have been written by
respected experts in their fields. It is an invaluable reference
book for both basic and clinical researchers.