Immunotherapy Of Cancer: An Innovative Treatment Comes Of Age
by Yoshiyuki Yamaguchi /
2016 / English / PDF
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This timely book, published just as cancer immunotherapy comes of
age, summarizes the rationale, present status, and future
perspective for cancer immunotherapy. Included are explanations
of the constitution of the immune system and immunocheckpoints,
the mechanism of antigen presentation and recognition, valuable
modalities, clinical trials and guidance, personalization, and
biomarkers, all of which are essential for understanding the
success of cancer immunotherapy. This innovative therapy has
been investigated worldwide as the fourth line of cancer
treatment after the standard treatments of surgery, chemotherapy,
and radiotherapy. The progress in fundamental understanding of
tumor immunology and the recent advances in clinical trials have
opened new avenues with a cancer vaccine in 2010 and
immunocheckpoint modulation in 2011, with their approval already
granted in the United States. Today, there are no doubts, even
among experts in cancer chemotherapy and radiotherapy, that the
immune system plays a vital role in tumor eradication. Following
American approval, many clinical trials of cancer
immunotherapy are being conducted.
This timely book, published just as cancer immunotherapy comes of
age, summarizes the rationale, present status, and future
perspective for cancer immunotherapy. Included are explanations
of the constitution of the immune system and immunocheckpoints,
the mechanism of antigen presentation and recognition, valuable
modalities, clinical trials and guidance, personalization, and
biomarkers, all of which are essential for understanding the
success of cancer immunotherapy. This innovative therapy has
been investigated worldwide as the fourth line of cancer
treatment after the standard treatments of surgery, chemotherapy,
and radiotherapy. The progress in fundamental understanding of
tumor immunology and the recent advances in clinical trials have
opened new avenues with a cancer vaccine in 2010 and
immunocheckpoint modulation in 2011, with their approval already
granted in the United States. Today, there are no doubts, even
among experts in cancer chemotherapy and radiotherapy, that the
immune system plays a vital role in tumor eradication. Following
American approval, many clinical trials of cancer
immunotherapy are being conducted. With this book the reader will readily understand the
paradigm shift in cancer treatment and will realize the importance
of cancer immunotherapy. The great value of immunotherapy will be
obvious, not only for tumor shrinkage but for prolonging patient
survival.
With this book the reader will readily understand the
paradigm shift in cancer treatment and will realize the importance
of cancer immunotherapy. The great value of immunotherapy will be
obvious, not only for tumor shrinkage but for prolonging patient
survival.