Mglu Receptors (the Receptors)
by Giuseppe Di Giovanni /
2017 / English / EPUB
2.2 MB Download
Metabotropic glutamate receptors (mGluRs) are members of the group
C family of G-protein-coupled receptors. Eight different mGlu
subtypes have been identified and classified into three groups
based on amino acid sequence similarity, agonist pharmacology, and
the signal transduction pathways to which they couple. They perform
a variety of functions in the central and peripheral nervous
systems, being involved in learning, memory, anxiety, and the
perception of pain. They are found in pre- and postsynaptic neurons
in synapses of the hippocampus, cerebellum, and cerebral cortex, as
well as other parts of the bain and peripheral tissues. This volume
will focus on the latest research in the role of Group I mGluRs in
health and disease.
Metabotropic glutamate receptors (mGluRs) are members of the group
C family of G-protein-coupled receptors. Eight different mGlu
subtypes have been identified and classified into three groups
based on amino acid sequence similarity, agonist pharmacology, and
the signal transduction pathways to which they couple. They perform
a variety of functions in the central and peripheral nervous
systems, being involved in learning, memory, anxiety, and the
perception of pain. They are found in pre- and postsynaptic neurons
in synapses of the hippocampus, cerebellum, and cerebral cortex, as
well as other parts of the bain and peripheral tissues. This volume
will focus on the latest research in the role of Group I mGluRs in
health and disease.
