Principles Of Cancer Genetics, 2nd Edition
by Fred Bunz /
2016 / English / PDF
9.2 MB Download
A concise guide to understanding the genes that cause cancer
Illuminates the respective contributions of heredity, the environment, and errors in DNA replication
Relates cancer genes to the hallmark characteristics of the cancer cell
Provides an overview of the genetic etiology of common cancers
Highlights new frontiers in gene-based risk analysis, diagnosis and therapy
This is the second edition of a widely used textbook that consolidates the basic concepts of the cancer gene theory and provides a framework for understanding the genetic basis of cancer. Particular attention is devoted to the origins of the mutations that cause cancer, and the application of evolutionary theory to explain how the cell clones that harbor cancer genes tend to expand. Focused on the altered genes and pathways that cause the growth of the most common tumors, Principles of Cancer Genetics is aimed at advanced undergraduates who have completed introductory coursework in genetics, biology and biochemistry, medical students and medical house staff. For students with a general interest in cancer, this book provides a highly accessible and readable overview. For more advanced students contemplating future study in the field of oncology and cancer research, this concise book will be useful as a primer.
