Protein Chaperones And Protection From Neurodegenerative Diseases
by Stephan N. Witt /
2011 / English / PDF
23.5 MB Download
How protein chaperones protect cells from neurodegenerativediseases Including contributions from leading experts, Protein Chaperonesand Protection from Neurodegenerative Diseases provides an in-depthexploration of how protein chaperones are involved in shieldingcells from toxic aggregated or misfolded protein states that causeALS, Parkinson's, and related diseases. Examining how different protein chaperones ameliorate thetoxicity of proteins that are known to cause neurodegenerativedamage, the book addresses both research and clinical perspectiveson chaperone and anti-chaperone properties. The intersection ofmolecular chaperones and neurodegeneration is an intensely studiedarea, partly because of the potential for manipulating theexpression of molecular chaperones to thwart the progression ofdebilitating diseases, and partly because of the ever-aging globalpopulation. Discussing the potential to harness the power of proteinchaperones, and future directions for research, discovery, andtherapeutics, this book is essential reading for scientists workingin the fields of biochemistry, molecular medicine, pharmacology anddrug discovery, biotechnology and pharmaceutical companies,advanced students, and anyone interested in this cutting-edgetopic.
