Protein Targeting Compounds: Prediction, Selection And Activity Of Specific Inhibitors (advances In Experimental Medicine And Biology)
by Thomas Böldicke /
2016 / English / PDF
5.5 MB Download
This book presents an overview of the most relevant protein
knockdown techniques. Readers will find a description of the
generation and use of recombinant human antibodies, ER
intrabodies and peptides as well as a description of the working
mechanism and potential of the inhibitory action of each of these
molecules. The book will also describe the selection and activity
of a number of phosphatases, aptamers and allosteric modulators,
focusing on A G protein coupled receptors. The book starts with a
chapter on the
This book presents an overview of the most relevant protein
knockdown techniques. Readers will find a description of the
generation and use of recombinant human antibodies, ER
intrabodies and peptides as well as a description of the working
mechanism and potential of the inhibitory action of each of these
molecules. The book will also describe the selection and activity
of a number of phosphatases, aptamers and allosteric modulators,
focusing on A G protein coupled receptors. The book starts with a
chapter on thein silico
in silico prediction of
target-inhibitor interactions.
prediction of
target-inhibitor interactions.
Key aspects of this book are:
Key aspects of this book are:
- Selection strategies for monoclonal and recombinant human
antibodies
- Selection strategies for monoclonal and recombinant human
antibodies
- Selection strategies for ER intrabodies, peptides and aptamers
- Selection strategies for ER intrabodies, peptides and aptamers- Examples of the most efficient inhibitors and their
applications in protein biochemistry and cell biology
- Examples of the most efficient inhibitors and their
applications in protein biochemistry and cell biology
- Antibodies for cancer therapy and inhibitors of angiogenesis.
- Antibodies for cancer therapy and inhibitors of angiogenesis.
The book will be of great interest to scientists and students
working in the life sciences on all areas related to protein
biology. The variety of methods to modulate the activities
of specific proteins which are introduced here will be of great
benefit to the reader who is interested in general protein
research or to readers who have very specific protein related
questions.
The book will be of great interest to scientists and students
working in the life sciences on all areas related to protein
biology. The variety of methods to modulate the activities
of specific proteins which are introduced here will be of great
benefit to the reader who is interested in general protein
research or to readers who have very specific protein related
questions.
