Proteomics For Drug Discovery: Methods And Protocols (methods In Molecular Biology)
by Iulia M. Lazar /
2017 / English / EPUB
4.8 MB Download
This book reflects the drug development community’s interest in
proteomics methods by providing researchers with the necessary
knowledge for the implementation of a number of basic experimental
and bioinformatics protocols in the drug discovery research
laboratory. The focus of the collection is on select protocols and
methodologies that address the analysis of post-translational
modifications, targeted protein quantification, protein-protein,
protein-lipid, or protein-ATP interactions, in
silico
This book reflects the drug development community’s interest in
proteomics methods by providing researchers with the necessary
knowledge for the implementation of a number of basic experimental
and bioinformatics protocols in the drug discovery research
laboratory. The focus of the collection is on select protocols and
methodologies that address the analysis of post-translational
modifications, targeted protein quantification, protein-protein,
protein-lipid, or protein-ATP interactions, in
silicolead identification, protein arrays, tissue and
cell extract preparation, labeling, chemoproteomics, and drug
efficacy assessment. Emphasis was placed not just on methods that
describe large-scale protein analysis, but also on ones that are
amenable to future implementation in a high-throughput format.
Written in the highly successful
lead identification, protein arrays, tissue and
cell extract preparation, labeling, chemoproteomics, and drug
efficacy assessment. Emphasis was placed not just on methods that
describe large-scale protein analysis, but also on ones that are
amenable to future implementation in a high-throughput format.
Written in the highly successfulMethods in Molecular
Biology
Methods in Molecular
Biology series format, chapters include introductions to
their respective topics, lists of the necessary materials and
reagents, step-by-step, readily reproducible laboratory protocols,
and tips on troubleshooting and avoiding known pitfalls.
series format, chapters include introductions to
their respective topics, lists of the necessary materials and
reagents, step-by-step, readily reproducible laboratory protocols,
and tips on troubleshooting and avoiding known pitfalls.
Practical and authoritative,
Practical and authoritative,Proteomics for Drug
Discovery: Methods and Protocols
Proteomics for Drug
Discovery: Methods and Protocols aims to provide a deep
knowledge of the fundamentals of disease biology as well the
means that were developed for probing the complex biological
milieu.
aims to provide a deep
knowledge of the fundamentals of disease biology as well the
means that were developed for probing the complex biological
milieu.
