Proteostasis And Chaperone Surveillance
by Parvaiz Ahmad /
2015 / English / PDF
4.7 MB Download
Proteostasis is central to the development of various human
diseases caused due to excessive protein misfolding and
the disregulation of the protein quality control system. In this
book, respected researchers from many leading institutions
contribute their insights on proteostasis maintenance. The
coverage mainly focuses on the basics of maintaining
proteostasis, the consequences of proteostatic system failure,
and how chaperone systems constantly maintain proteostasis. In
addition, the book presents in detail different treatment
strategies for diseases caused by proteostatic system failure, as
well as the inhibition of proteostatic failure using small
molecule compounds. It examines advances in the modulation of
proteopathies, providing a comprehensive source of key
mechanistic insights on these diseases. As such, the book offers
a valuable resource for beginners and more experienced
investigators alike who are looking for detailed and reliable
information on protein homeostasis, the diseases that can develop
due to related imbalances and the essential role of molecular and
chemical chaperones.
Proteostasis is central to the development of various human
diseases caused due to excessive protein misfolding and
the disregulation of the protein quality control system. In this
book, respected researchers from many leading institutions
contribute their insights on proteostasis maintenance. The
coverage mainly focuses on the basics of maintaining
proteostasis, the consequences of proteostatic system failure,
and how chaperone systems constantly maintain proteostasis. In
addition, the book presents in detail different treatment
strategies for diseases caused by proteostatic system failure, as
well as the inhibition of proteostatic failure using small
molecule compounds. It examines advances in the modulation of
proteopathies, providing a comprehensive source of key
mechanistic insights on these diseases. As such, the book offers
a valuable resource for beginners and more experienced
investigators alike who are looking for detailed and reliable
information on protein homeostasis, the diseases that can develop
due to related imbalances and the essential role of molecular and
chemical chaperones.