Regenerative Medicine: Laboratory To Clinic
by Asok Mukhopadhyay /
2017 / English / PDF
9.4 MB Download
This book discusses the two different cellular approaches that
are pursued in regenerative medicine: cell therapy and tissue
engineering. It examines in detail the therapeutic application of
hematopoietic stem cells in marrow regeneration, multi-potent
mesenchymal stem cells (MSCs), also referred to as mesenchymal
stromal cells. The interest in MSCs can be seen in more than 150
clinical trials, some of which have progressed to Phase III,
despite the cells’ limited differentiation potential. The book
also explores how embryonic stem (ES) cells, being pluripotent in
nature, can resolve some of the problems associated with adult
stem cells, yet entail other challenges like risks of teratoma
formation and immune rejection. A separate chapter deals with the
role of noncoding RNAs in neuronal commitment of induced
pluripotent stem (iPS) cells.
This book discusses the two different cellular approaches that
are pursued in regenerative medicine: cell therapy and tissue
engineering. It examines in detail the therapeutic application of
hematopoietic stem cells in marrow regeneration, multi-potent
mesenchymal stem cells (MSCs), also referred to as mesenchymal
stromal cells. The interest in MSCs can be seen in more than 150
clinical trials, some of which have progressed to Phase III,
despite the cells’ limited differentiation potential. The book
also explores how embryonic stem (ES) cells, being pluripotent in
nature, can resolve some of the problems associated with adult
stem cells, yet entail other challenges like risks of teratoma
formation and immune rejection. A separate chapter deals with the
role of noncoding RNAs in neuronal commitment of induced
pluripotent stem (iPS) cells.Chapters like “Cord blood banking in India and the global
scenario”; “3D bioprinting of tissue” and others will make this
book an extremely interesting read for all students, researchers
and clinicians working in the area of regenerative medicine/stem
cells.
Chapters like “Cord blood banking in India and the global
scenario”; “3D bioprinting of tissue” and others will make this
book an extremely interesting read for all students, researchers
and clinicians working in the area of regenerative medicine/stem
cells.
The book is broadly divided into two parts, the first of which is
devoted to basic information on stem cells, and the second of
which addresses potential clinical applications in the areas of
hematology, cardiology, orthopedic and immune suppression, etc.
The book is broadly divided into two parts, the first of which is
devoted to basic information on stem cells, and the second of
which addresses potential clinical applications in the areas of
hematology, cardiology, orthopedic and immune suppression, etc.
