Ribosome-Inactivating Proteins: Ricin And Related Proteins
by Douglas Lappi /
2014 / English / PDF
7.4 MB Download
This important reference provides up–to–date information on all aspects of ribosome–inactivating proteins (RIPs). Including a list of all known RIPs, their distribution in nature, structure, genetics and chemical and immunological properties, this reference covers mechanisms of action, including the enzymatic activity on various polynucleotide substrates; the interaction with, and entry into cells; the toxicity to animals, including the pathology of poisoning; and the immunomodulatory and allergenic activity. The book further emphasizes the use of immunotoxins and other conjugates in clinical trials for the therapy of cancer and intractable pain.
