Single Nucleotide Polymorphisms: Methods And Protocols (methods In Molecular Biology)
by Anton A. Komar /
2009 / English / PDF
7.5 MB Download
In recent years, single nucleotide polymorphisms have received
increased and special attention in a rapidly developing field of
personalized medicine and drug treatment. Comprising more than
eighty percent of all known polymorphisms, single nucleotide
polymorphisms (SNPs) are primarily responsible for phenotypic
differences between individuals, and have been suggested to
affect the development of diseases in humans and the response to
drug treatment and environmental stress. In
In recent years, single nucleotide polymorphisms have received
increased and special attention in a rapidly developing field of
personalized medicine and drug treatment. Comprising more than
eighty percent of all known polymorphisms, single nucleotide
polymorphisms (SNPs) are primarily responsible for phenotypic
differences between individuals, and have been suggested to
affect the development of diseases in humans and the response to
drug treatment and environmental stress. InSingle Nucleotide
Polymorphisms: Methods and Protocols, Second Edition
Single Nucleotide
Polymorphisms: Methods and Protocols, Second Edition, expert
researchers explore the latest advances in this area,
highlighting the substantial progress that has been made in SNP
genotyping, examining recent developments in high-throughput
genotyping approaches, and exploring our new understanding of the
impact of SNPs on gene function. Chapters address the impact of
SNPs on phenotype, examine SNP databases, look at methods that
have been applied for SNP bioinformatics discovery and analysis,
and discuss advanced experimental approaches used for SNP
detection. Composed in the highly successful
, expert
researchers explore the latest advances in this area,
highlighting the substantial progress that has been made in SNP
genotyping, examining recent developments in high-throughput
genotyping approaches, and exploring our new understanding of the
impact of SNPs on gene function. Chapters address the impact of
SNPs on phenotype, examine SNP databases, look at methods that
have been applied for SNP bioinformatics discovery and analysis,
and discuss advanced experimental approaches used for SNP
detection. Composed in the highly successfulMethods in
Molecular Biology
Methods in
Molecular Biology™ series format, each chapter contains a
brief introduction, step-by-step methods, a list of necessary
materials, and a Notes section which shares tips on
troubleshooting and avoiding known pitfalls.
™ series format, each chapter contains a
brief introduction, step-by-step methods, a list of necessary
materials, and a Notes section which shares tips on
troubleshooting and avoiding known pitfalls.
Current and innovative,
Current and innovative,Single Nucleotide Polymorphisms:
Methods and Protocols,
Single Nucleotide Polymorphisms:
Methods and Protocols,Second Edition
Second Edition is an
essential guidebook for individual researchers as well as
institutions and companies working in the field.
is an
essential guidebook for individual researchers as well as
institutions and companies working in the field.