Snake Venoms (toxinology)
by P. Gopalakrishnakone /
2017 / English / EPUB
5.9 MB Download
Initially, because of the inadequate sensitivity of devices and
other limitations, only major venom components of the dominant
species were studied. However, in last two decades, increased
sensitivity of devices and the development of new techniques,
such as transcriptomics and proteomics techniques, have permitted
us to analyze the structures and functions of rare species and to
identify novel minor components. As a result, the number of venom
components identified is increasing dramatically and the
physiological functions of each component is more deeply
understood. The scope of this book provides the readers an
updated and comprehensive presentation on snake venoms. The
subjects are divided into six sections, starting with the
overview of snake venom compositions in Malaysian species,
followed by description of enzymes and enzyme inhibitors
contained in snake venoms. Also discussed are the effects of
snake venom on cellular receptors, ion channels, blood, and
lymph, as well as cytotoxic and antimicrobial molecules present
in snake venoms. The last section covers the clinical
consequences of envenomation and the management of snakebites
using antivenins.
Initially, because of the inadequate sensitivity of devices and
other limitations, only major venom components of the dominant
species were studied. However, in last two decades, increased
sensitivity of devices and the development of new techniques,
such as transcriptomics and proteomics techniques, have permitted
us to analyze the structures and functions of rare species and to
identify novel minor components. As a result, the number of venom
components identified is increasing dramatically and the
physiological functions of each component is more deeply
understood. The scope of this book provides the readers an
updated and comprehensive presentation on snake venoms. The
subjects are divided into six sections, starting with the
overview of snake venom compositions in Malaysian species,
followed by description of enzymes and enzyme inhibitors
contained in snake venoms. Also discussed are the effects of
snake venom on cellular receptors, ion channels, blood, and
lymph, as well as cytotoxic and antimicrobial molecules present
in snake venoms. The last section covers the clinical
consequences of envenomation and the management of snakebites
using antivenins.