Stem Cells In Modeling Human Genetic Diseases (stem Cell Biology And Regenerative Medicine)
by Mayana Zatz /
2015 / English / PDF
4.4 MB Download
While most stem cell books focus on basic aspects and/or cell
therapy, this book emphasizes the relevance of stem cells obtained
from patients, the so-called “patients in a petri dish” as
tools to investigate human genetic diseases for which there are no
available effective treatment. Chapters embrace several examples of
the use of iPS cell technology, a recent Nobel Prize-winning
scientific breakthrough, to obtain patient-specific pluripotent
cells from which many types of specialized cells involved in a
particular disease can be generated, including psychiatric and
neurodegenerative disorders, muscular dystrophies, laminopathies,
among others. The text is a current and timely resource for
postgraduate students, scientists and clinicians, interested in
applications of this rapidly developing field of research in
disease modeling, drug development, and emerging issues that it
brings to regenerative medicine.
While most stem cell books focus on basic aspects and/or cell
therapy, this book emphasizes the relevance of stem cells obtained
from patients, the so-called “patients in a petri dish” as
tools to investigate human genetic diseases for which there are no
available effective treatment. Chapters embrace several examples of
the use of iPS cell technology, a recent Nobel Prize-winning
scientific breakthrough, to obtain patient-specific pluripotent
cells from which many types of specialized cells involved in a
particular disease can be generated, including psychiatric and
neurodegenerative disorders, muscular dystrophies, laminopathies,
among others. The text is a current and timely resource for
postgraduate students, scientists and clinicians, interested in
applications of this rapidly developing field of research in
disease modeling, drug development, and emerging issues that it
brings to regenerative medicine.
