Sudden Cardiac Death In The Young And Athletes: Text Atlas Of Pathology And Clinical Correlates
by Gaetano Thiene /
2016 / English / PDF
36.9 MB Download
This text atlas focuses on the pathology and molecular genetics
of sudden cardiac death in the young and in athletes, presenting
the state of the art in the field as the basis for development
and implementation of more effective prevention strategies,
including, ultimately, molecular therapy that will cure the
underlying biological defect. A wealth of high-resolution
color images, accompanied by clear supporting text, are presented
to document the anatomic pathology of the cardiac diseases most
frequently responsible for sudden cardiac death in this
population, including coronary artery diseases, cardiomyopathies,
myocarditis, valve diseases, conduction system abnormalities,
congenital heart diseases, and ion channel diseases. The role of
the molecular autopsy in overcoming the limitations of
morphological investigations and offering new insights and
avenues for prevention is explained. The approach is, however,
interdisciplinary, with close attention also to epidemiologic and
clinical aspects. The authors draw throughout on their experience
gained over 30 years in the course of a prospective study
carried out in the Veneto Region, North East Italy. This text
atlas will be of great value not only for cardiologists but also
for geneticists, sports physicians, and residents in cardiology
and pathology.
This text atlas focuses on the pathology and molecular genetics
of sudden cardiac death in the young and in athletes, presenting
the state of the art in the field as the basis for development
and implementation of more effective prevention strategies,
including, ultimately, molecular therapy that will cure the
underlying biological defect. A wealth of high-resolution
color images, accompanied by clear supporting text, are presented
to document the anatomic pathology of the cardiac diseases most
frequently responsible for sudden cardiac death in this
population, including coronary artery diseases, cardiomyopathies,
myocarditis, valve diseases, conduction system abnormalities,
congenital heart diseases, and ion channel diseases. The role of
the molecular autopsy in overcoming the limitations of
morphological investigations and offering new insights and
avenues for prevention is explained. The approach is, however,
interdisciplinary, with close attention also to epidemiologic and
clinical aspects. The authors draw throughout on their experience
gained over 30 years in the course of a prospective study
carried out in the Veneto Region, North East Italy. This text
atlas will be of great value not only for cardiologists but also
for geneticists, sports physicians, and residents in cardiology
and pathology.