Telomeres And Telomerase In Aging, Disease, And Cancer: Molecular Mechanisms Of Adult Stem Cell Ageing
by K. Lenhard Rudolph /
2007 / English / PDF
3.8 MB Download
Telomere shortening represents one of the basic aspects of ageing
and telomere dysfunction could contribute to the accumulation of
DNA damage during ageing. This book summarizes evidence and data
indicating that telomere dysfunction influences human ageing,
diseases and cancer. The book describes our current knowledge on
checkpoints that limit cellular lifespan and survival in response
to telomere dysfunction. There is special focus on adult stem
cells.
Telomere shortening represents one of the basic aspects of ageing
and telomere dysfunction could contribute to the accumulation of
DNA damage during ageing. This book summarizes evidence and data
indicating that telomere dysfunction influences human ageing,
diseases and cancer. The book describes our current knowledge on
checkpoints that limit cellular lifespan and survival in response
to telomere dysfunction. There is special focus on adult stem
cells.
