Tobacco Smoke Exposure Biomarkers
by Hongwei Hou /
2015 / English / PDF
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Written by experts in the analytical chemistry of tobacco smoke, Tobacco Smoke Exposure Biomarkers summarizes the toxicology, metabolic pathway, and biomarkers of nicotine, TSNAs, PAHs, VOCs, AAs, Catechol and Hydroquinone, HCN, CO and NOx, and heavy metals. The book then details the use of therse biomarkers in exposure assessment and/or cigarette smoke exposure environmental epidemiology. Lead author Qingyuan Hu, China's sole representative to the relevant WHO study group as well as the Tobacco Laboratory network, gives you unique insight into China's view on tobacco product regulation. The book discusses nicotine and its metabolite cotinine as biological markers to determine tobacco smoking in smokers and estimate exposure to environmental tobacco smoke to non-smokers. It also examines leading classes of carcinogens in tobacco products and tools for risk assessment of exposure. The authors then detail the volatile organic compounds produced from the combustion of cigarettes, the generation of carcinogenic primary aromatic amines, and the toxicity of catechols. They highlight exposure to heavy metals such as cadmium, mercury, lead, and arsenic from smoking. A convenient one-stop guide, the book brings together information on some exposure biomarkers and nicotine addiction in humans with regulatory implications and strategies. The authors also include discussions of how smoke exposure biomarkers may be used to shape regulation and health policy. Ethics guidelines, details of method development, and the validated relative bioanalytical method provided in the appendixes rounds out the coverage. The book gives you tools to further research biomarkers for tobacco carcinogens and to face emerging health challenges such as delivery of nicotine via electronic cigarettes.
