Using Old Solutions To New Problems: Natural Drug Discovery In The 21St Century Ed. By Marianna Kulka

Using Old Solutions To New Problems: Natural Drug Discovery In The 21St Century Ed. By Marianna Kulka
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This book is a collection of an expert team of agronomists, chemists, biologists and policy makers who discuss some of the processes involved in developing a naturally-sourced bioactive compound into a drug therapy. These experts define a natural compound and elucidate the processes required to find, extract and define a naturally-derived bioactive molecule, they describe the necessity for understanding the fundamental mechanisms of disease before applying bioactive molecules in bioassay-guided drug discovery platforms The medicinal use of plants, animals and microorganisms has been a part of human evolution and likely began before recorded history. Is it possible that this knowledge can be used to create powerful new drugs and solve some of the human health problems facing us today? Preface Section 1 Agronomy and Molecular Characterization 1 Discovery, Development, and Regulation of Natural Products 2 Genetic, Agronomy, and Metabolomics of Prince Edwards Island Wild Rose Collection and Promise for Cultivar Development 3 Magnetic Resonance Technologies: Molecules to Medicine Section 2 Bioactive Proteins from Natural Sources 4 Marine Natural Products for Protein Misfblding Modulation 5 Marine Flatfish-Derived Bioactive Peptides: From the Ocean to the Bedside Section 3 Bioactive Ingredients in Nutrition 6 Anticancer Properties of Phytochemicals Present in Medicinal Plants of North America 7 A New Perspective on the Development of Cholesterol-Lowering Products 8 A Glance at the Complexity of Nutrition and the Prostate: Considering Molecular Targets to Unravel the Most Recent Controversy Between Omega-3 Fatty Acids and Their Impact on Prostate Cancer Risk Section 4 Bioactive Compounds in Health and Disease 9 Mechanisms and Treatment of Photoaging and Photodamage 10 Asthma in the 21st Century — Unexpected Applications of Ancient Treatments 11 Plant Based Natural Products and Breast Cancer: Considering Multi-Faceted Disease Aspects, Past Successes, and Promising Future Interventions

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