Bacterial Cellular Metabolic Systems: Metabolic Regulation Of A Cell System With 13c-metabolic Flux Analysis (woodhead Publishing Series In Biomedicine)
by Kazuyuki Shimizu /
2013 / English / PDF
7.1 MB Download
The metabolic regulation of a cell system is of critical
importance in systems biology. A robust model of these
mechanisms is essential in predicting the effects on the
metabolism of both the culture environment and the knockout of
specific genes. The author focuses on this highly topical subject
in relation to culture environment and provides a detailed
analysis from gene level to metabolic level regulation, as well
as offering a discussion of the most recent modelling approaches.
Chapters introduce metabolic mechanisms and the metabolic
regulation of a cell, discuss the action of global
regulators in response to a specific culture environment and
examine conventional flux balance analysis and its applications,
13C-metabolic flux analysis, and the effect of a specific gene
knockout on the metabolism.
The metabolic regulation of a cell system is of critical
importance in systems biology. A robust model of these
mechanisms is essential in predicting the effects on the
metabolism of both the culture environment and the knockout of
specific genes. The author focuses on this highly topical subject
in relation to culture environment and provides a detailed
analysis from gene level to metabolic level regulation, as well
as offering a discussion of the most recent modelling approaches.
Chapters introduce metabolic mechanisms and the metabolic
regulation of a cell, discuss the action of global
regulators in response to a specific culture environment and
examine conventional flux balance analysis and its applications,
13C-metabolic flux analysis, and the effect of a specific gene
knockout on the metabolism.
